According to Ephesians 5:18, instead of getting drunk on wine, believers should be filled with what?

Answer: The Spirit

Paul warns that drunkenness leads to reckless indiscretion and says, "Instead, be filled with the Spirit."

“Do not get drunk on wine, which leads to reckless indiscretion. Instead, be filled with the Spirit.”— Ephesians 5:18 (BSB)